Publications

  1. Weaver K, Skouta R. (2022) The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities. Biomedicines.  
  2. Dhuguru J, Zviagin E, Skouta R. (2022) FDA-Approved Oximes and Their Significance in Medicinal Chemistry. Pharmaceuticals. 
  3. Skouta R. (2021) What Did We Accomplish in Fighting Radical Species in Human Health? Antioxidants. 
  4. Dhuguru J, Skouta R. (2020) Role of Indole Scaffolds as Pharmacophores in the Development of Anti-Lung Cancer Agents. Molecules.
  5. Ko PJ, Woodrow C, Dubreuil MM, et al. (2019)A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death. Cell Chem Biol.
  6. Ruiz-Medina BE, Lerma D, Hwang M, Ross JA, Skouta R, Aguilera RJ, Kirken RA, Varela-Ramirez A, Robles-Escajeda E. (2019) Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways, Scientific Reports.
  7. Contreras L, Calderon RI, Varela-Ramirez A, Zhang HY, Quan Y, Das U, Dimmock JR, Skouta R, Aguilera RJ. (2018) Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones., Cellular Oncology
  8. Morán-Santibañez K, Peña-Hernández MA, Cruz-Suárez LE, Ricque-Marie D, Skouta R, Vasquez AH, Rodríguez-Padilla C, Trejo-Avila LM (2018) Virucidal and Synergistic Activity of Polyphenol-Rich Extracts of Seaweeds against Measles Virus. Viruses.
  9. Skouta, R.; Morán-Santibañez, K.; Valenzuela, C.; Vasquez, A.; Fenelon, K. (2018) Assessing the Antioxidant Properties of Larrea tridentata Extract as a Potential Molecular Therapy against Oxidative Stress., Molecules.
  10. Rodriguez, Felipe; Iniguez, Eva; Contreras, Guadalupe Pena; Ahmed, Haidar; Costa, Thadeu E. M. M.; Skouta, Rachid; Maldonado, Rosa A. (2018) Development of Thiophene Compounds as Potent Chemotherapies for the Treatment of Cutaneous Leishmaniasis Caused by Leishmania major, Molecules.
  11. Shimada, K.; Skouta, R.; Kaplan, A.; Yang, W.; Hayano, M.; Dixon, S.; Brown, L.; Valenzuela, C.; Wolpaw, A.; Stockwell, B. (2016) Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis., Nature Chemistry Biology
  12. Skouta, R. (2016) Neuroprotective effect of antioxidant compounds. Neural Regeneration Research. (NRR)
  13. Khalil, M.; Valenzuela, C.; Sisniega, D.; Skouta, R.; Narayan, M. (2016) ER Protein Processing Under Oxidative Stress: Implications and Prevention., Cell Biochemistry and Biophysics.
  14. Iniguez, E.; Perez, A.; Maldonado, R.; Skouta, R. (2015) Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania major., Bioorganic & Medical Chemistry Letters (BMCL).
  15. Kabiraj, R.; Valenzuela C.; Marin, J.; Ramirez, D.; Mendez, L.; Hwang, M.; Varela-Ramirez, A.; Fenelon, K.; Narayan, M.; Skouta, R. (2015) The neuroprotective role of ferrostatin-1 under rotenone-induced oxidative stress in dopaminergic neuroblastoma cells., The Protein Journal.
  16. Linkermann, A.; Skouta, R.; Himmerkus, N,; Mulay, S.; Dewitz, C.; De Zen, F.; Prokai, A.; Zuchtriegel, G.; Krombach, F.; Welz, P.; Weinlich, R.; Vanden Berghe, T.; Vandenabeele, P.; Pasparakis M.; Bleich, M.; Weinberg, J.; Reichel, C.; Bräsen, J.; Kunzendorf, U.; Anders, H.; Stockwell, B.; Green, D.; Krautwald, S. (2014) Synchronized renal tubular cell death involves ferroptosis., Proceedings of the National Academy of Sciences of the United States of America (PNAS).
  17. Yang, W.; SriRamaratnam, R.; Welsch, M.; Shimada, K.; Skouta, R.; Viswanathan, V.; Cheah, J.; Clemons, P.; Shamji, A.; Clish, C.; Brown, L.; Girotti, A.; Cornish, V.; Schreiber, S.; Stockwell, B. (2014) Regulation of ferroptotic cancer cell death by GPX4., Cell.
  18. Dixon, S.; Patel, D.; Welsch, M.; Skouta, R.; Lee, E.; Hayano, M.; Thomas, M.; Gleason, C.; Tatonetti, N.; Slusher, B.; Stockwell, B. (2014) Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis., eLife.
  19. Skouta, R.; Dixon, S,; Wang, J.; Dunn, D.; Orman, M; Shimada, K,; Rosenberg P.; Lo D.; Wienberg, J.; Linkermann, A.; Stockwell, B. (2014) Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models., Journal of the American Chemical Society (JACS)
  20. Skouta, R.; Hayano, M.; Shimada, K.; Stockwell, B. (2012) Design and synthesis of Pictet-Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death., Bioorganic & Medicinal Chemistry Letters (BMCL).
  22. Yang, W.; Shimada, K.; Delva, D.; Patel, D.; Ode, E.; Skouta, R.; Stockwell, B. (2012) Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency., ACS Medicinal Chemistry Letters.
  23. Wolpaw, A.; Shimada, K.; Skouta, R.; Welsch, M.; Akavia, U.; Pe’er, D.; Shaik, F. Bulinski, J.; Stockwell B. (2011) Modulatory profiling identifies mechanisms of small molecule-induced cell death., Proceedings of the National Academy of Sciences of the United States of America (PNAS)
  24. Schneebeli, S.; Kamenetska, M.; Cheng, Z.; Skouta, R.; Friesner, R.; Venkataraman, L.; Breslow, R. (2011) Single-molecule conductance through multiple π-π-stacked benzene rings determined with direct electrode-to-benzene ring connections., Journal of American Chemistry Society (JACS)
  25. Schneebeli, S.; Kamenetska, M.; Foss, F.; Vazquez, H.; Skouta, R.; Hybertsen, M.; Venkataraman L.; Breslow, R. (2010) The electrical properties of biphenylenes., Organic Letters.
  26. Skouta, R.; Wei, S.; Breslow, R. (2009) High rates and substrate selectivities in water by polyvinylimidazoles as transaminase enzyme mimics with hydrophobically bound pyridoxamine derivatives as coenzyme mimics., Journal of American Chemistry Society (JACS).
  27. Wei, S.; Wang, J.; Venhuizen, S.; Skouta, R.; Breslow, R. (2009) Dendrimers in solution can have their remote catalytic groups folded back into the core: enantioselective transaminations by dendritic enzyme mimics-II., Organic & Biomolecular Chemistry.
  28. Yu, M,; Skouta, R.; Zhou, L.; Jiang, HF.; Yao, X.; Li, CJ. (2009) Water-triggered, counter-anion-controlled, and silver-phosphines complex-catalyzed stereoselective cascade alkynylation/cyclization of terminal alkynes with salicylaldehydes., The Journal of Organic Chemistry (JOC).
  29. Zhou, L.; Chen, L.; Skouta, R.; Jiang, HF.; Li, CJ. (2008) Palladium-catalyzed 1,4-addition of terminal alkynes to unsaturated carbonyl compounds promoted by electron-rich ligands., Organic & Biomolecular Chemistry.
  30. Skouta, R.; Li, CJ. (2007) Gold(I)-catalyzed annulation of salicylaldehydes and aryl acetylenes as an expedient route to isoflavanones., Angewandte Chemie
  31. Baillargeon, P; Bernard, S.; Skouta, R.; Dory, YL. (2007) Efficient synthesis and astonishing supramolecular architectures of several symmetric macrolactams., Organic & Biomolecular Chemistry.
  32. Leclair, S.; Baillargeon, P.; Skouta, R.; Gauthier, D.; Zhao, Y.; Dory, YL. (2004) Micrometer-sized hexagonal tubes self-assembled by a cyclic peptide in a liquid crystal., Angewandte Chemie.